- Jan 8 St. Laurence Justinian [Lorenzo Giustiniani], Italian catholic bishop and 1st Patriarch of Venice, dies at 74
- May 1 Hugues de Lannoy, Flemish viceroy of Holland/Zealand, dies
- May 24 Ambroise de Loré, French military commander (b. 1396)
- Aug 11 Janos Hunyadi, Hungarian general strategist, dies at about 49
- Oct 23 Saint John of Capistrano, Franciscan friar and Catholic priest from the Italian town of Capestrano, Abruzzo, dies at 70
- Nov 3 Edmund Tudor, 1st Earl of Richmond and patriarch of the Tudor Dynasty, dies of bubonic plague imprisoned in Carmarthen Castle at 26
- Nov 25 Jacques Coeur, French merchant/banker, dies in battle