- Jan 18 Emperor Go-Hanazono, 102nd Emperor of Japan, dies at 51
- Feb 21 John of Rokycan, Czech Catholic archbishop
- Mar 12 Dionysius the Carthusian [Denis Ryckel], Flemish scholastic theologist, dies at 69
- Mar 22 George van Podiebrad, king of Bohemia (1458-71), dies
- Mar 24 Thomas Malory, author (Le Morte d'Arthur), dies at 55
- Apr 14 Richard Neville [16th Earl of Warwick], English nobleman and military commander known as Warwick the Kingmaker, slain in battle at 42
- May 1 Thomas a Kempis, German Dutch spiritual writer (Navolging of Christ), dies at 91
- May 4 Edward of Westminster, Prince of Wales, dies at 17, becoming the only heir apparent to the English throne to ever die in battle
- May 4 Edmund Beaufort, 4th Duke of Somerset, English military commander (executed)
- May 21 King Henry VI of England (1422-1471) is executed in the Tower of London at 49
- Jul 25 John Soreth, French general, dies
- Jul 26 Pope Paul II [Pietro Barbo], Italian Pope (1464-71), dies at 54
- Dec 17 Isabella of Portugal, duchess of Burgundy, dies