- Apr 9 Lorenzo de' Medici (the Magnificent), leading Florentine statesman and patron of the arts during Florentine Renaissance, dies at 43
- Jun 7 Casimir IV Jagiellon, King of Poland (1447-92), dies at 64
- Jun 16 Jan Coppenhole, Flemish rebel leader, beheaded
- Jul 25 Innocent VII [Giovanni B Cibo], Italian Pope (1484-92), dies
- Oct 12 Piero della Francesca, Italian painter
- Nov 9 Jami [Mowlanā Nūr Od-dīn ʿabd Or-raḥmān Ebn Aḥmad], Persian poet (Lava'ih), dies at 78