- Jan 9 John Haynes, 5th Governor of the Massachusetts Bay Colony, dies at 58
- Feb 21 Adriaen Pauw, master of Heemstede and Dutch Grand Pensionary, dies at 71
- Mar 23 Johan van Galen, Dutch admiral (commanded Dutch fleet during Battle of Leghorn), dies of wounds from the Battle of Leghorn at about 48
- May 10 John Bicker, ship builder/merchant/regent, dies at 61
- May 18 Carel Reyniersz, Governor General of the Dutch East Indies, dies at 48
- May 19 Carel Reyniersz, gov-gen of Neth East Indies, dies at 48
- May 26 Robert Filmer, English writer (b. 1588)
- Jul 10 Gabriel Naudé, French librarian and scholar (b. 1600)
- Jul 31 Thomas Dudley, British colonial governor of Massachusetts, dies at 76
- Aug 10 Maarten Tromp, Dutch admiral, dies in battle at 55
- Aug 29 Gillesz de Hondecoeter, painter/Hostage rights, buried at about 49
- Sep 3 Claudius Salmasius [Claude Saumaise], French linguist, dies at 65
- Sep 20 Humphrey Chetham, English cloth merchant (his will leaves money to establish Chetham Library - oldest English language public library in the world), dies at 72 [1]
- Oct 3 Mark Zuesius Boxhorn, Dutch historian, dies at 41
- Oct 7 Fausto Poli, Italian Catholic priest (b. 1581)
- Nov 26 Maximilian Teellinck, vicar, dies at about 51