- Jan 21 Nicolas-Francois Blondel, French architect, dies
- Jan 31 Jean Mairet, French dramatist famous for tragedies (Sophonisbe) and comedies, dies at 81
- Feb 8 Francois Tak, Dutch diplomat on Java, murdered
- Feb 10 William Dugdale, English antiquarian and Garter King of Arms (1677-86), dies at 80
- Feb 24 Ferdinando Tacca, Italian painter/son of Pietro Tacca, dies at 66
- Feb 26 Godefroi L Comte d'Estrades, French diplomat/marshal, dies at about 78
- Apr 6 Arthur Annesley, 1st Earl of Anglesey, English royalist statesman, dies at 71
- Apr 19 Antonio de Solís y Ribadeneyra, Spanish writer (b. 1610)
- May 21 Otto von Guericke, German scientist, inventor, and politician, dies at 83
- Jun 6 Joannes B van Neercassel, RC spiritual leader of Neth, dies at 60
- Jun 23 William Coventry, English statesman
- Jun 25 Simon Ushakov, Russian icon painter (b. 1626)
- Jul 10 Ercole Ferrata, Italian sculptor/restaurateur, dies at 76
- Jul 10 John Fell, English churchman (b. 1625)
- Jul 11 Michel Anguier, French sculptor, dies at 75
- Jul 16 John Pearson, English theologian (b. 1612)
- Aug 13 Louis Maimbourg, French-born historian (b. 1610)
- Oct 8 Adriaen Paets, Rotterdam regent and diplomat, dies at about 55
- Oct 26 John Egerton, 2nd Earl of Bridgewater, English politician, dies at 63
- Dec 5 Nicolas Steno, Danish scientist prominent in anatomy and geology, and later Catholic priest, bishop, and candidate for sainthood, dies at 48
- Dec 6 Eleonora Gonzaga, Empress of the Holy Roman Empire (1651-57), dies at 56
- Dec 11 Louis II Condé, Duke of Bourbon (Rocroy), dies at 65