- Jan 27 Louis Henri, Duc de Bourbon, Prime Minister of France, dies at 47
- Feb 6 Clement XII [Lorenzo Corsini], Italian Pope (1730-40) who despite ill health and total blindness (1732) unsuccessfully stemmed decline of papal influence, dies at 87
- Feb 29 Pietro Ottoboni, Italian cardinal and grandnephew of Pope Alexander VIII, dies at 72
- Apr 23 Thomas Tickell, English writer and poet, dies at 54
- Apr 25 Shrimant Baji Rao Vishwanath Bhat, also known as Baji Rao I, a general and Peshwa (b. 1699)
- May 15 Ephraim Chambers, English encyclopaedist (b. 1680)
- May 17 Jean Cavalier, French Huguenot chief of the Camisards, dies at 58
- May 31 Frederik Willem I, King of Prussia (1713-1740), dies at 51
- Jun 1 Samuel Werenfels, Swiss theologian (b. 1657)
- Jun 6 Alexander Spotswood, British governor of Virginia Colony
- Jun 17 Sir William Wyndham, English politician (b. 1687)
- Jul 6 Claudius Amyand, French-born British surgeon who performed first appendectomy, dies at about 80
- Jul 19 Francois van Aerssen, Dutch vice-admiral (Suriname, Algeria), dies at 71
- Oct 5 Johann Philipp Baratier, German scholar (b. 1721)
Charles VI
Oct 20 Charles VI, Holy Roman Emperor (1711-40), dies after falling ill on a hunting trip at 55
Charles VI