- Jan 3 Ferdinando Galli-Bibiena, Italian architect and designer, dies at 85
- Jan 7 Anne Sophie Reventlow, Queen of Denmark and Norway (1721-30), dies at 49
- Jan 29 Andre Hercule Fleury, French cardinal (1726-43), dies
- Feb 18 Anna Maria Luisa de' Medici, last of the Medicis (b. 1667)
- Apr 4 Daniel Neal, English historian, dies at 64
- Apr 16 Cornelis van Bijnkershoek, Dutch jurist who helped develop international law along positivist lines, dies at 69
- Apr 29 Charles-Irénée Castel de Saint-Pierre, French writer (b. 1658)
- Apr 30 Pedro de Peralta y Barnuevo, Peruvian poet (Obras Dramaticas), dies at 79
Spencer Compton
Jul 2 Spencer Compton 1st Earl of Wilmington, Prime Minister of Great Britain (Whig: 1742-43) statesman who served in government from 1715 until his death, dies at about 70
- Aug 1 Richard Savage, English poet and playwright, dies at about 46
- Aug 5 John Hervey, 2nd Baron Hervey, English statesman and writer (b. 1696)
- Sep 14 Nicolas Lancret, French painter (b. 1690)
- Sep 21 Jai Singh II, King of Amber-Juiper (b. 1688)
- Oct 4 John Campbell, 2nd duke of Argyll and field marshal (Union of 1707), dies at 64
- Dec 27 Hyacinthe Rigaud, French painter, dies at 84