- Apr 4 Mary Mead, wife of English radical and journalist John Wilkes (b. 1715)
- Apr 10 Simon Fokke, book illustrator, dies at 71
- Apr 26 (Honora) "Nano" Nagle, Irish Catholic educator and religious order founder (Sisters of the Presentation of the Blessed Virgin Mary, aka Presentation Sisters) dies of tuberculosis at about 66.
- Apr 30 Franz K earl von Velbruck, German free mason, dies