- Apr 3 George Pocock, British admiral (b. 1706)
- Apr 4 James Sykes, American politician (b. 1725)
- Apr 14 Maximilian Hell, Slovakian astronomer (b. 1720)
- Apr 21 Tiradentes, Brazilian revolutionary (b. 1746)
- Apr 23 Karl Friedrich Bahrdt, German theologian and adventurer, dies at 50
- Apr 25 Nicolas J Pelletier, French highwayman, 1st person guillotined
- Apr 30 John Montagu, 4th Earl of Sandwich, British statesman who claimed to have invented the sandwich, dies at 73