Elizabeth Ann Seton
Jan 4 Elizabeth Ann Bayley Seton, 1st native-born American saint, dies in Maryland at 46
John Keats
Feb 23 John Keats, English Romantic poet (Ode to a Grecian Urn), dies of tuberculosis at 25
- Feb 23 Marie-Anne Collot, French sculptor, dies
- Feb 26 Joseph de Maistre, Savoyard diplomat and writer (b. 1753)
- Apr 20 Franz Karl Achard, German physicist and chemist, dies at 67
- Apr 21 Thursday October Christian, son of Fletcher Christian (leader of the historical mutiny on the Bounty), dies at 40
- Apr 22 John Crome [Old Crome], English landscape painter & etcher, dies at 52
Napoléon Bonaparte
May 5 Napoleon Bonaparte, French military leader and Emperor of the French (1804-14, 1815), dies in exile on the island of Saint Helena, officially from stomach cancer but rumours of arsenic poisoning persist
- May 19 Camille Jordan, French politician (b. 1771)
- Jun 7 Tudor Vladimirescu, Romanian rebellion-leader (b. cca. 1780)
- Jun 13 Alexander Gogel, Dutch minister of Finance, dies at 55
- Jun 17 Martín Miguel de Güemes Argentine military leader (b. 1785)
- Jul 4 Richard Cosway, English portrait painter, dies at 78
- Jul 21 Maurice J M prince de Broglie, bishop of Ghent, dies at about 55
- Aug 4 William Floyd, American soldier who signed the US Declaration of Independence, dies at 86
- Aug 7 Caroline of Brunswick, Queen Consort of King George IV (1820-21), dies at 53
José Miguel Carrera
Sep 4 José Miguel Carrera, 1st President of Chile (1811-14), shot and killed after a show trial at 35
- Sep 27 Luis Brión, Curacaos military officer who fought in the Venezuelan War of Independence, dies at 39
- Oct 4 John Rennie, Scottish engineer, dies at 60
- Oct 11 John Ross Key, American lawyer, commissioned officer in the Continental Army and the father of Francis Scott Key, dies at 67
- Oct 24 Elias Boudinot, American lawyer and patriot, President of the Continental Congress, dies at 81
- Dec 12 Phoebe Hessel, English woman who disguised herself as a man to serve in the British Army, probably to be with her lover, Samuel Golding, dies at 108
- Dec 29 Jean-Baptiste Dumonceau, Dutch general, dies at 61