- Jan 14 Franz Innocenz Joseph Kobell, German landscape painter, dies at 72
- Feb 5 Ali Paşa Tepelenë, known as 'The Lion of Janina", Ottoman Albanian ruler, Pasha of Yanina (1788-1822), dies aged somewhere between 78-82
- Feb 10 Albert Casimir, Duke of Teschen and Governor of the Austrian Netherlands, dies at 83
- Feb 24 Thomas Coutts, Anglo-Scottish banker (Coutts & Co.), dies at 86
- Apr 3 Friedrich Bertuch, writer, dies
- May 8 John Stark, American military officer (Battle of Bennington), dies at 93
- May 17 Armand-Emmanuel, Duc de Richelieu, Prime Minister of France (1815-18, 1820-21), dies at 55
- Jul 2 Denmark Vesey, American carpenter and ex-slave, head of a planned slave revolt, hanged with 5 others at Blake's Landing, Charleston, South Carolina at about 55
- Jul 8 Percy Bysshe Shelley, English romantic poet (Prometheus unbound), drowns at 29
- Aug 12 Robert Stewart, 2nd marguess of Londonderry, commits suicide, dies
Jean Baptiste Joseph Delambre
Aug 19 Jean Baptiste Joseph Delambre, French mathematician and astronomer, dies at 72
Jean Baptiste Joseph Delambre
William Herschel
Aug 25 William Herschel, German-British astronomer (discovered Uranus), dies at 83
William Herschel
- Oct 13 Antonio Canova, Italian sculptor, dies at 64
- Oct 29 Dirk van Hogendorp, Dutch minister of War, dies at 61
- Nov 6 Hendrik van Stralen, Secretary of Interior, dies at 71
- Nov 6 Claude Louis Berthollet, French chemist (b. 1748)
- Nov 19 Johann Georg Tralles, German mathematician and physicist (b. 1763)