Johann Wolfgang von Goethe
Mar 22 Johann Wolfgang von Goethe, German writer and social philosopher (Faust), dies at 82

Johann Wolfgang von Goethe
Georges Cuvier
May 13 Georges Cuvier [Jean Léopold Nicolas Frédéric Cuvier], French naturalist and zoologist, dies at 62

Georges Cuvier
- May 14 John van Speijk, Dutch heroic sailor, buried
- May 31 Évariste Galois, French mathematician (Group theory), dies at 20
- Jun 6 Jeremy Bentham, English philosopher (b. 1748)
- Jun 23 James Hall, Scottish geologist, dies at 70
- Jul 22 Napoleon II of France (b. 1811), son of Napoleon I dies of tuberculosis
- Jul 30 Jean-A-C Chaptal, French chemist/Internal minister, dies
- Aug 24 Nicolas Léonard Sadi Carnot, French mathematician (b. 1796)
- Sep 2 Franz Xaver, Baron Von Zach, Austrian astronomer, dies at 78
- Sep 21 Walter Scott, Scottish historical novelist and poet (The Lady of the Lake, Ivanhoe), dies at 61
- Sep 27 Karl Christian Friedrich Krause, German philosopher, dies at 51
- Nov 14 Charles Carroll, Wealthy Maryland planter who was the last signer of the Declaration of Independence to pass away, dies at 95
- Nov 14 Rasmus Rask, Danish linguist and philologist (Investigation of the Origin of the Old Norse or Icelandic Language), dies of tuberculosis at 44
- Nov 15 Jean Baptiste Say, French economist, dies at 63
- Dec 30 Abijah Hammond, owned large portion of Greenwich Village, dies