William Grenville
Jan 12 William Grenville, 1st Baron Grenville, Prime Minister of the United Kingdom (Whig: 1806-07), dies at 74
- Jan 16 Jean Nicolas Pierre Hachette, French mathematician (b. 1769)
- Jan 17 Giovanni Aldini, Italian physicist, dies at 71
- Feb 6 Richard Lemon Lander, British explorer, dies from his injuries sustained by a musket ball at 29
- Feb 12 Friedrich Schleiermacher, German theologist and philosopher, dies at 65
- Feb 16 Lionel Lukin, British life boat pioneer, dies at 91
- Mar 12 Karl Wilhelm Feuerbach, German mathematician (circle of Feuerbach), dies at 33
- May 20 Marie-Joseph-Paul-Yves-Roch-Gilbert de Motier, nobleman, dies
Marquis de Lafayette
May 20 Marquis de Lafayette, American patriot and French revolutionary, dies at 76
- Jun 9 William Carey, one of the founders of the Baptist Missionary Society (b. 1761)
- Jun 10 Antonius van Gils, Dutch Roman Catholic theologist (against Relief), dies at 75
- Jun 28 Joseph Bové, Russian architect (b. 1784)
- Jul 14 Edmond Charles Genêt, French ambassador to the United States during the French Revolution (b. 1763)
Samuel Taylor Coleridge
Jul 25 Samuel Taylor Coleridge, British romantic poet (Rime of Ancient Mariner), dies of heart failure at 61
- Jul 26 Jonathan Jennings, American politician (Governor of Indiana, 1816–1822; Congressman for Indiana, 1822–1831), dies at 50
- Aug 1 Robert Morrison, missionary in China/translated bible, dies
- Aug 5 Gijsbert Karel van Hogendorp, Dutch count and Minister of Foreign affairs (1813-14), dies at 71
- Aug 7 Joseph Marie Jacquard, French weaver and inventor (b. 1752)
- Aug 17 Husein Gradaščević, Bosniak general, dies at 31
- Sep 2 Thomas Telford, Scottish civil engineer (designed and constructed Menai Bridge, Wales in 1819-26), dies at 77
- Sep 16 Antoine-Vincent Arnault, French writer (Guillaume the Nassau), dies
- Sep 24 Pedro I of Brazil, Emperor of Brazil (1822-31) and King of Portugal (1826), dies at 35
- Oct 10 Thomas Say, American naturalist and father of descriptive entomology, dies from typhoid fever at 47
- Oct 19 Cornelis Loots, Dutch accountant and poet (Volkswoede), dies at 69
- Oct 31 Éleuthère Irénée du Pont, French-American chemist and industrialist (E. I. du Pont de Nemours and Company), dies at 63
- Nov 5 Aernout Drost, Dutch literary/founder (The Guide), dies at 24
- Dec 6 Jonas Daniel Meyer, Dutch lawyer, dies at 54
Thomas Malthus
Dec 23 Thomas Malthus, British economist and demographer (Law of Malthus), dies of heart disease at 68
- Dec 27 Charles Lamb, British critic/poet/essayist (Essays of Elia), dies at 59