- Mar 14 Thirty Years' War: Bavaria, Cologne, France and Sweden sign the Truce of Ulm.
- Mar 25 Cape of Good Hope: tour ship Haerlem stranded in Tafel Bay
- May 11 Peter Stuyvesant arrives in New Amsterdam
- May 23 Willem II sworn in as viceroy of Holland
- May 26 Massachusetts disallows priest access to colony
- May 26 Alse Young becomes the first person executed as a witch in the American colonies, when she is hanged in Hartford, Connecticut
- Jun 4 English Parliamentary army under Cornet George Joyce takes King Charles I as a prisoner during Second Civil War
- Jul 7 People's uprising against high prices and Spanish rule in Naples
- Aug 8 The Irish Confederate Wars and Wars of the Three Kingdoms: Battle of Dungans Hill - English Parliamentary forces defeat Irish forces.
- Sep 1 French cardinal Mazarin & Duke of Modena sign treaty against Milan
- Nov 11 Massachusetts passes first compulsory school attendance law in the American colonies