Events in Sport
- May 1 136th Kentucky Derby: Calvin Borel wins aboard Super Saver, his third Derby success in 4 years
- May 9 Oakland A's Dallas Braden becomes 19th pitcher to throw a perfect game (4-0 vs Tampa Bay)
- May 15 135th Preakness: Martin Garcia aboard Lookin At Lucky wins in 1:55.47
- May 22 18th UEFA Champions League Final: Internazionale beats Bayern Munich 2-0 at Madrid
- May 23 NHL Western Conference Finals: Chicago Black Hawks beat San Jose Sharks, 4 games to 0
- May 24 NHL Eastern Conference Final: Philadelphia Flyers beat Montreal Canadians, 4 games to 1
- May 29 Philadelphia Phillies' Roy Halladay becomes 20th pitcher to throw a perfect game (1-0 vs Florida)
- May 30 Indianapolis 500: Dario Franchitti wins in 3:05:37.0131 (260.107 km/h)
Deaths in Sport
- May 4 Ernie Harwell, American sportscaster (b. 1918)
- May 6 Robin Roberts, American baseball player (b. 1926)
- May 15 Loris Kessel, Swiss racing driver (b. 1950)
- May 15 Besian Idrizaj, Footballer (b. 1987)
- May 23 Jose Lima, Dominican baseball player (b. 1972)
- May 24 Morrie Martin, Major League Baseball pitcher (b. 1922)
- May 25 Alexander Belostenny, Ukrainian basketball player (b. 1959)
- May 25 Alan Hickinbotham, Australian businessman, football player, & football coach (b. 1925)
- May 26 Jarvis Williams, American football player (b. 1965)