- Sep 1 Finnish long distance runner Viljo Heino runs 10,000m world record 29:27.2 in Kouvola, Finland
- Sep 5 US National Championship Men's Tennis: Pancho Gonzales beats fellow American Ted Schroeder 16-18, 2-6, 6-1, 6-2, 6-4; longest singles final match by games (67), before tiebreaker introduction
- Sep 5 US National Championship Women's Tennis, Forest Hills, NY: Defending champion Margaret Osborne duPont beats fellow American Doris Hart 6-4, 6-1
- Sep 13 Ladies Pro Golf Association of America formed in NYC
- Sep 17 Ryder Cup Golf, Ganton GC: US beats Great Britain, 7-5; Americans win 6 of 8 singles matches to claim victory
- Sep 18 Baseball major league record 4 grand slams hit
- Sep 20 Top American tennis player Pancho Gonzales turns professional
US Women's Golf Open
Sep 25 US Open Women's Golf, Prince George's CC: Louise Suggs leads wire-to-wire to win by 14 strokes ahead of runner-up and defending champion Babe Zaharias
Louise Suggs
- Sep 25 Despite 71 injuries, Yankees have been in 1st place all season until Red Sox move into a tie for 1st place